PHYTO-CANNABINOIDS

 

Within the cannabis plant, dozens of active compounds are found inside the stem, flower and leaf. 70 unique cannabinoids have been identified by researchers within this cannabis plant.


Tetrahydrocannabinolic Acid (THCA)

• The main feature in raw cannabis
• THCA, when vaporised or heated to a certain temperature this converts to A9-THC
• Cannabinoids such as THCA, CBDA, CBGA and other acidics maintain the largest values

Tetrahydrocannabinol (THC)

• This is well-known for its most psychoactive effects
• Please be aware that not all forms of cannabis contain THC

Cannabidiolic Acid (CBDA)

• This is similar to THCA which is the main ingredient contained within different varieties of the hemp plant. This is mainly found within the flower of the plant, it is the persecutor to cbd, which when heated it loses its acid molecule and convers into cbd

Cannabidiol (CBD)

• When the correct ratio of CBD is applied to treat a particular deficiency, CBD has tremendous potential
• CB1 and CB2 receptors act as an antagonist with CBD and yet it has a low binding affinity for both
• Suggesting that CBD's mechanism of action is mediated by other receptors in the brain and body

Cannabinol (CBN)

• Produced from the degradation of THC, CBN is a mild psychoactive cannabinoid

Cannabigerol (CBG)

• This is a non-psychoactive cannabinoid which acts as a low affinity antagonist at the CB1 receptor
• CBG pharmacological activity is currently unknown within the CB2 receptor

Cannabichromene (CBC)

CBC is most frequently found in tropical cannabis varieties. The effects of CBC appear to be mediated through non-cannabinoid receptor interactions.

Tetrahydrocannabivarin (THCV)

THCV is a minor cannabinoid found in only some strains of cannabis. The only structural difference between THCV and THC is the presence of a propyl (3 carbon) group, rather than a pentyl (5 carbon) group, on the molecule. Though this variation may seem subtle, it causes THCV to produce very different effects than THC. THCV acts as an antagonist at the CB1 receptor and a partial agonist at the CB2 receptor.

Cannabidivarin (CBDV)

Like THCV, CBDV differs from CBD only by the substitution of a pentyl (5 carbon) for a propyl (3 carbon) sidechain.